Method of making 3,5-difluoroaniline from 1,3,5-trichlorobenzene

Details Method of making 3,5-difluoroaniline from 1,3,5-trichlorobenzene Method of making 3,5-difluoroaniline from 1,3,5-trichlorobenzene

2000-02-08

2000-10-03

Barts, Samuel

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C20910

Patent

active

061275778

ABSTRACT:
A method for manufacturing 3,5-difluoroaniline by fluorinating 1,3,5-trichlorobenzene and then aminating the intermediate fluorinated benzene with aqueous or anhydrous ammonia to achieve the product in yields of greater than 80%.

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Pews, R.G., "Aromatic Fluorine Chemistry, Part 4, Preparation of 2,6-Difluoroaniline", J. Fluorine Chem., (1991), pp. 307-316, vol. 52, Month Available.

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