Method of maintaining the fluidity of hormone solutions for pare

Details Method of maintaining the fluidity of hormone solutions for pare Method of maintaining the fluidity of hormone solutions for pare

1980-07-22

1981-12-22

Michell, Robert W.

Surgery

Respiratory method or device

Ozone or ion generation

128213R, A61M 500

Patent

active

043065538

ABSTRACT:
A method of preventing the precipitation of hormone preparations within drug delivery systems that depend on the fluidity of the infusate for proper function. A non-toxic water soluble detergent is dissolved in the hormone solution prior to the introduction of the solution into the drug delivery system. The detergent is added in amount sufficient to prevent precipitation of the hormone during long-term storage in the drug delivery device. According to one form of usage, the hormone-detergent solution is charged to the pressurized drug storage chamber of an implanted infusion pump by injection through the patient's skin. As the solution is discharged from the delivery device by the constant pressure exerted upon the storage chamber, its low rate of flow is controlled by a restricted fluid passage. The solution is conveyed to an infusion site and diluted by the blood stream.

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