Method of maintaining or improving a nitrile hydratase activity

Details Method of maintaining or improving a nitrile hydratase activity Method of maintaining or improving a nitrile hydratase activity

2007-07-17

2007-07-17

Lilling, Herbert J. (Department: 1657)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

C435S232000, C435S252330

Reexamination Certificate

active

10850374

ABSTRACT:
The object of this invention is to provide a method which not only maintains the nitrile hydratase activity of a nitrile hydratase-containing cell or a treated material of the cell under conditions where the cell does not grow, but also improves the nitrile hydratase activity of a nitrile hydratase-containing cell or a treated material of the cell whose activity was once reduced. This invention relates to a method of maintaining or improving a nitrile hydratase activity which comprises bringing a nitrile hydratase-containing cell or a treated material of the cell into contact with an oxidizing agent under conditions where the cell does not grow, as well as a method of producing an amide compound from a nitrile compound, which comprises using the cell brought into contact with an oxidizing agent or a treated material of the cell.

REFERENCES:
patent: 5179014 (1993-01-01), Watanabe et al.
patent: 5705382 (1998-01-01), Endo et al.
patent: 6132985 (2000-10-01), Pierce
patent: 6316242 (2001-11-01), Endo et al.
patent: 43 13 649 (1995-01-01), None
patent: 0 707 061 (1996-04-01), None
M. Odaka; M. Tsujimura; and I. Endo, “Post-translational modifications in nitrile hydrates family”, RIKEN Review No. 41, Nov. 20001, pp. 58-60.
O. Masafumi, T. Masanari; and I. Endo, “Structure and function of iron-type nitrile hydratases: an inhibition study”, New Development of Reaction in Organic Chemistry, No. 3, 2001, pp. 17-20.
P. K. Mascharak, “Structural and functional models of nitrile hydratase”, Coordination Chemistry Reviews, No. 225, 2002, pp. 201-214.
Patent Abstract of Japan 05-043351, Date of Publication Jul. 1, 1993 (cited in specification).
Patent Abstract of Japan 04-048435, Date of Publication Aug. 6, 1992 (cited in specification).
Patent Abstract of Japan 08-112089, Date of Publication May 7, 1996 (cited in specification).
Patent Abstract of Japan 02-000035, Date of Publication Jan. 5, 1990 (cited in specification).
Patent Abstract of Japan 2002-017339, Date of Publication Jan. 22, 2002 (cited in specification).
Nojiri et al., “Cobalt-substituted Fe-type nitrile hydratase ofRhodococcussp. N-771,”FEBS Letters, Jan. 14, 2000, pp. 173-177, vol. 465, No. 2-3, Elsevier Science Publishers, Amsterdam, NL.
Search Report dated Aug. 4, 2005 in corresponding French Application No. 0405712000.

Affiliated with

Also associated with

Rating

Method of maintaining or improving a nitrile hydratase activity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of maintaining or improving a nitrile hydratase activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of maintaining or improving a nitrile hydratase activity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3727589