Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1979-02-28
1980-10-28
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
210222, G01N 3100, G01N 2146
Patent
active
042306850
ABSTRACT:
Magneticaly-responsive microspheres having Protein A associated with the outer surfaces thereof are reacted with antibodies selective to the cells, bacteria, or viruses to be separated from a mixed population to attach the antibodies in oriented relation with their Fab arms extending outwardly, and the microspheres are then used in a magnetic separation procedure. The preferred microspheres are prepared from a mixture of albumin, Protein A, and magnetic particles, the microspheres being prepared so that the Protein A is present in the exterior surfaces for antibody binding.
REFERENCES:
patent: 3970518 (1976-07-01), Giaever
patent: 4018886 (1977-04-01), Giaever
Kessler-Dissertation Abst. Int(B), 1976, vol. 37, No. 3, pp. 1172-1173.
Senyei Andrew E.
Widder Kenneth J.
Northwestern University
Waddell Frederick E.
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