Method of lowering cholesterol

Details Method of lowering cholesterol Method of lowering cholesterol

1995-03-15

1996-04-23

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

552625, 552626, A61K 3156

Patent

active

055103421

ABSTRACT:
This invention provides a method of lowering cholesterol and blood lipid levels, preventing hypercholesterolemia, hyperlipidemia, cardiovascular disease, atherosclerosis, and peripheral vascular disease comprising administering an effective amount of 17.alpha.-dihydroequilenin or a mammalian metabolic conjugate thereof to a mammal in need thereof.

REFERENCES:
patent: 4154820 (1979-05-01), Simoons
patent: 4826831 (1989-05-01), Plunkett
patent: 4894373 (1990-01-01), Young
Lobo, R. A., Fertility and Sterility 49:234 (1988).
Walsh, B. W., The New England Journal of Medicine 325:1196 (1991).
Novakovic, J., Journal of Pharmaceutical & Biomedical Anal. 8:253 (1990).
Glen, W. L., Nature 177: 753 (1956).
Howard, R. P., Arch. Intern. Med. 128:229 (1971).
Stern, M. D., Maturitas 4:333 (1982).
Stern, M. D., Endometrial Cancer, Brush, ed., 309 (1978).
Grant, G. A., Recent Prog. Horm. Res. 5: 307 (1950).
Bhavnani, B. R., Steroids 56:201 (1991).
Bhavnani, B. R. J. Clin. Endocrin. Metab. 56: 1048 (1983).
Bhavnani, B. R., Endocrin. 108:232 (1981).
Lyman, G. W., Chrom. 14: 234 (1982).
Ross, R. K., Am. J. Obstet. Gynecol. 160: 1301 (1989).
Barrett-Connor, E., JAMA 261: 2095 (1989).
Lobo, R. A., Obstet. Gynecol. 75: 18S (1990).
Stampfer, M. J., N. E. J. Med. 313: 1044 (1985).
Barrett-Connor, E., Annu. Rev. Med. 43: 239 (1992).
Barrett-Connor, E., JAMA 265:1861 (1991).
Bhavnani, B. R., J. Steroid Biochem. 17: 217 (1982).
Levy, R., Am. Heart J. 110: 1116 (1985).
Ross, R., New Eng. J. Med. 295: 369 (1977).
Ross, R., New Eng. J. Med. 314: 488 (1986).
Manderson, J. A., Arteriosclerosis 9: 289 (1989).
Clowes, A. W., Circ. Res. 56: 139 (1985).
Clowes, W. W., J. Cardiovas. Pharm. 14 (Suppl 6): S12 (1989).
Barrett-Connor, E., JAMA 265: (1991).
Chao, Y-S., J. Biol. Chem. 254: 11360 (1979).
Kovanen, P. T., J. Biol. Chem. 254: 11367 (1979).
Windler E. E. T., J. Biol. Chem., 255: 10464 (1980).
Utian, W. H., Obstet. Gynecol. Surv. 32: 193 (1977).
ACOG Technical Bulletin 93: 1 (1986).
Hammond, C. B., Fertil. Steril. 37: 5 (1982).
Whitehead, M. I., Am. J. Obstet. Gynecol. 142: 791 (1982).
Gambrell, R. D., South Med. J. 71: 1280 (1978).
McDonald T. W., Am. J. Obstet. Gynecol. 127: 572 (1977).
Whitehead, M. I., J. R. Soc. Med. 72: 322 (1979).

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