Method of lowering blood cholesterol level

Details Method of lowering blood cholesterol level Method of lowering blood cholesterol level

1976-07-01

1978-05-30

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

A61K 2700

Patent

active

RE0296520

ABSTRACT:
The level of blood cholesterol in a living animal body in which a state of hypercholesterolemia exists is lowered by orally administering to said animal body a pharmaceutically effective amount of a polymer, which is (1) polymerized unsaturated carboxylic acid or anhydride, or (2) a copolymer of (a) an unsaturated monomer having, for Example, 2 to 30 carbon atoms and, (b) an unsaturated carboxylic acid, anhydride or derivative thereof as exemplified by octadecene-1/maleic anhydride copolymer. Polymers having lipophilic properties are a preferred class. A typical dosage is an amount which represents in the range of from about 0.01 to about 5.0% of the diet.

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Cavallini et al., Potential Anticholesterine-Mic Antirheumatic Drugs, 7/5/57, vol. 79, pp. 3514-3517.
Tennent et al., J. Lipid Research, 10/16, vol. 5, pp. 469-470.

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