Method of locating or imaging activated T-lymphocytes with a tar

Details Method of locating or imaging activated T-lymphocytes with a tar Method of locating or imaging activated T-lymphocytes with a tar

1986-10-21

1989-05-23

Terapane, John F.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 4, 424 5, 424 71, A61K 4900, A61K 4902, A61K 4904

Patent

active

048329401

ABSTRACT:
The present invention provides targeting polypeptides for use in targeting and identifying activated T-lymphocytes in the human or animal body, the targeting polypeptides being capable of binding specifically to the interleukin-2 receptors of activated T-lymphocytes or to molecules associated with the receptors and carrying one or more physiologically compatible imaging agents. Such targeting polypeptides can be used for, example, in the location of tumours and abscesses and other inflammatory conditions and in the monitoring of tissue transplants for possible rejection.

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