Method of localizing nucleic acids bound to polyamide supports

Details Method of localizing nucleic acids bound to polyamide supports Method of localizing nucleic acids bound to polyamide supports

1985-07-26

1988-10-04

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

436501, 935 77, 935 78, 935 87, C12N 1500

Patent

active

047756314

ABSTRACT:
A method of detecting and localizing nucleic acids on polyamide supports which comprises contacting said supports with a suspension of colloidal metal particles whereupon the metal particles bind to the polyamide support and form a colored background against which the location where nucleic acids are present become visible as lighter spots. The method enables the mere qualitative localization of the nucleic acids and the quantitative determination thereof following art-known procedures.

REFERENCES:
patent: 4455370 (1984-06-01), Bartelsman
Moeremans, Analytical Biochemistry 145, 315-321 (1985).

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