Method of lightening skin

Details Method of lightening skin Method of lightening skin

1998-12-17

1999-11-23

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Cosmetic, antiperspirant, dentifrice

424 59, 424 62, 424 63, 4241951, 514844, 514946, A61K 7135, A61K 7021, A61K 3578

Patent

active

059895764

ABSTRACT:
A method and composition for the topical application of a yohimbine or derivative or stereoisomer thereof or effective .alpha..sub.2 -antagonists, to the skin for inhibiting melanogenesis in the skin leading to skin lightening. The yohimbine may be provided as a natural extract, for example, as an extract of Johimbe bark.

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patent: 5705170 (1998-01-01), Kong et al.
F. Morishita, "Responses of the Melanophores of the Medaka, Oryzias Latipes, to Adrnergic Drugs: Evidence for Involvement of Alpha.sub.2 Adrenergic Receptors Mediating Melanin Aggregation", Comp. Biochem. Physiol., 88C(1):69-74, 1987.

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