Method of labeling proteins with technetium

Details Method of labeling proteins with technetium Method of labeling proteins with technetium

1975-11-26

1977-11-08

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

250303, 2523011R, 424 15, 424 9, A61K 3704, A61K 3300, A61K 4300

Patent

active

040576175

ABSTRACT:
Fibrinogen is labeled with .sup.99m Technetium by reducing pertechnetate at a pH of about 11-12 using a solution of stannous chloride in the presence of a base, then contacting the reduced pertechnetate with fibrinogen. Unwanted lower molecular weight impurities are removed; the labeled product suitably adjusted to a pH of 7-8 to form an injectable isotopic tracer solution.

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