Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1997-10-03
1998-12-29
Guzo, David
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
4352351, 435239, C12Q 170, C12N 700, C12N 702
Patent
active
058539824
ABSTRACT:
A method of isolating a gypsy moth virus that maintains normal levels of viral occlusion when produced in an insect cell line is disclosed. This method comprises the steps of cycles of infecting gypsy moth larvae with a strain of gypsy moth virus of interest, harvesting the larvae to collect budded virus, infecting a cell line capable of propagation in a bioreactor and then harvesting the virus. One repeats the infection cycle until one has enriched for a gypsy moth virus strain with normal levels of occlusion.
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Fado John D.
Guzo David
Silverstein M. Howard
Stockhausen Janet I.
The United States of America as represented by the Secretary of
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