Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-03-14
1999-03-16
Degen, Nancy
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 536 231, C12Q 168, G01N 3353, C07H 2100
Patent
active
058828664
ABSTRACT:
Methods of making nucleic acids that inhibit complex formation between antigen binding proteins and non-nucleic acid immunogens are provided. Methods of making non-nucleic acid immunogens that inhibit complex formation between antigen binding proteins and nucleic acids are also provided herein.
REFERENCES:
patent: 5270163 (1993-12-01), Gold et al.
patent: 5525495 (1996-06-01), Keene et al.
Tsai et al. In vitro selection of RNA epitopes using autoimmune patient serum. J. of Immunology vol. 150 pp. 1137-1145, 1993.
Gold et al. From oligonucleotide shapes to genomic SELEX: Novel biological regulatory loops. Proc. Natl. Acad. Sci. USA vol. 94 pp. 59-64, 1997.
Keene; RNAs Selected to RRM Proteins; Methods in Enzymology; 267:381-383, (May 17, 1996).
Edgington; Shape Space; Bio/Technology; 11:285-289, (Mar. 1993).
Deutscher and Keene; A sequence-specific conformational epitope on U1 RNA is recognized by a unique autoantibody; Proc. Natl. Acad. Sci. USA; 85:3299-3303, (May 1988).
Bock et al.; Selection of single-stranded DNA molecules that bind and inhibit human thrombin; Nature; 355:564-566, (Feb. 1992).
Doudna et al.; Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor; Proc. Natl. Acad. Sci., USA; 92:2355-2359, (Mar. 1995).
Reichlin et al.; Lupus Autoantibodies to Native DNA Cross-React with the A and D SnRNP Polypeptides; J. Clin. Invest.; 93:443-449, (Jan. 1994).
Gao et al.; Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1; Proc. Natl. Acad. Sci. USA; 91:11207-11211, (Nov. 1994).
Tuerk and Gold; Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase; Science; 249:505-510, (Aug. 3, 1990).
Tsai et al.; In vitro selection of an RNA epitope immunologically cross-reactive with a peptide; Proc. Natl. Acad. Sci. USA; 89:8864-8868, (Oct. 1992).
Brusca John S.
Degen Nancy
LandOfFree
Method of isolating ribotopes and proteotopes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of isolating ribotopes and proteotopes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of isolating ribotopes and proteotopes will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-816401