Method of isolating CA 125 antigen

Details Method of isolating CA 125 antigen Method of isolating CA 125 antigen

1986-11-24

1991-10-22

Draper, Garnette D.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530395, 530412, 530413, 530417, 530418, 530419, 530420, 530827, 530853, 530832, 530387, 435 701, 424 858, C07K 1500, C07K 328

Patent

active

050596802

ABSTRACT:
A preparation of an isolated immunoreactive CA 125 Antigen, and a method of isolating it is disclosed. CA 125 Antigen is a glycoprotein having a molecular weight of about 200kD, and a carbohydrate-content of about 24%. The CA 125 Antigen is isolated from a cell culture medium by acid precipitation, and is subsequently purified by size exclusion chromatography and immunoaffinity chromatography.

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