Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification
Patent
1992-12-21
1994-06-28
Nucker, Christine M.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Separation or purification
530395, 530413, 530414, 530828, 424 88, 424558, 424582, 424583, C07K 114, C07K 1514, A61K 3550
Patent
active
053248228
ABSTRACT:
A method of isolation of a material with similar immunological properties to CA-195 from human amniotic fluid has been disclosed. This material can be substituted for CA-195 in many processes, for example in the preparation of analytical control materials.
REFERENCES:
patent: 4229426 (1980-10-01), Haagensen
patent: 4376110 (1983-03-01), David et al.
patent: 4389392 (1983-06-01), Adachi
patent: 4440863 (1984-04-01), Haagensen, Jr.
patent: 4455380 (1984-06-01), Adachi
patent: 4486530 (1984-12-01), David et al.
patent: 4489166 (1984-12-01), Joshi
patent: 4571382 (1986-02-01), Adachi
patent: 4582787 (1986-04-01), Frankel
patent: 4687733 (1987-08-01), Trewyn et al.
patent: 4818709 (1989-04-01), Primus et al.
Fundamental Immunology, 1989, pp. 923-939 Schreiber, H. "Tumer Immunology".
Biegelmayer, C., et al. Tumor Biol 10:232-242 (Oct. 5, 1989) MCA, a monoclonal-antibody defined breast tumor-associated and its relation to CA 15.3.
Duffy, T. H., et al., Clinical Chemistry 35(6):1079 (Jul. 25, 1989), "Tumor markers in seminal plasma and amniotic fluid".
Gadler, H., Int. J. Cancer 25:91-94 (1980), "Distribution of tumor-associated antigen CEA and cross-reacting NCA in fetal organs".
Hyoty, M., et al., Eur. J. Surg. 158:173-179 (1992), "Tumour antigens CA 195 and CA 19-9 in pancreatic juice and serum for the diagnosis of pancreatic carcinoma".
Jacobs, I. J., et al., British J. Obstet. Gynacol. 95:1190-1194 (Nov. 1988), "The distribution of CA 125 in the reproductive tract of pregnant and non-pregnant women".
Lelle, R. J., et al., Gynecol. Obstet. Invest. 27:137-142 (1989), "Measurement of CEA, TPA, Neopterin, CA125, CA153, and CA199 in sera of pregnant women, umbilical cord blood and amniotic fluid".
Masson, P., et al., Int. J. Pancreatol. 8:333-344 (1991), "Evaluation of CEA, CA 19-9, CA-50, CA-195, and TATI with special reference to pancreatic disorders".
Wobbes, T., et al., Cancer 69(8):2036-2041 (Apr. 15, 1992), "Evaluation of seven tumor markers (CA 50, CA 19-9, CA 19-9 TruQuant, CA 72-4, CA 195, CEA and Tissue Polypeptide Antigen) in the pretreatment sear of patients with gastric cardinoma".
Bhargava, A. K. et al., Circulating CA-195 in Colorectal Cancer, 2 J. Tumor Marker Oncology (1987) 319.
Bray, K. R. et al., A Monoclonal Antibody that Detects a Tumor Associated Antigen in the Sera of Patients with Colon Cancer, 43 Federation Proceedings (1987) 1059.
Gupta, M. K. et al. CA-195: A New Sensitive Monoclonal Antibody-Defined Tumor Marker for Pancreatic Cancer, 2, J. Tumor Marker Oncology (1987) 201.
Gaur, P. K. et al., Relationship Between Cancer Associated Antigen 195 (CA-195) and CEA, 28 Proceedings of AACR (1987) 357.
Bray, K. R. et al., Serum Levels of Cancer-Associated Antigen 195, a Circulating Marker for Colon Cancer, and its Relationship to Carcinoembryonic Antigen, 2 Journal of Clinical Laboratory Analysis (1988) 187-193.
EP Search Report.
Ciba Corning Diagnostics Corp.
Cunningham T.
Morgenstern Arthur S.
Nucker Christine M.
Slepchuk, Jr. Nicholas I.
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