Method of inserting DNA into living cells

Details Method of inserting DNA into living cells Method of inserting DNA into living cells

1980-04-24

1983-07-19

Marantz, Sidney

Chemistry: molecular biology and microbiology

Treatment of micro-organisms or enzymes with electrical or...

Modification of viruses

424 19, 435317, 435820, C12N 1500

Patent

active

043944485

ABSTRACT:
A method of inserting deoxyribonucleic acid or fragments thereof into a living cell, which comprises; encapsulating the DNA or fragment in a lipid vesicle and bringing the vesicle in contact with said cell, whereby insertion occurs.

REFERENCES:
patent: 4186183 (1980-01-01), Steck
patent: 4217344 (1980-08-01), Vanlerberghe
patent: 4235871 (1980-11-01), Papahadjopoulos
patent: 4241046 (1980-12-01), Papahadjopoulos
R. T. Fraley et al., Proc. Natl. Acad. Sci. USA, 76 (7), 3348-3352 (Jul. 1979).
G. Gregoriadis, The New England Journal of Medicine, 295 (14), 765-769 (1976).
Chemical Abstracts, 82:119546r (1975).
Chemical Abstracts, 84:1325f (1976).
Chemical Abstracts, 85:137237g (1976).
Chemical Abstracts, 91:71257d (1979).

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