Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1996-09-26
1999-12-14
Chan, Christina Y.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
4241301, 4241331, 4241411, 4241431, 4241521, 4241531, 4241541, 4241721, 4241731, A61K 39395
Patent
active
060013567
ABSTRACT:
The present invention provides a method for preventing tissue destruction associated with autoimmune inflammatory diseases by utilizing anti-CD44 monoclonal antibodies to induce the loss of the CD44 receptor from cell surfaces, thus preventing the interaction between cell-surface CD44 and extracellular hyaluronan.
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Glant Tibor Tivadar
Mikecz Katalin
Chan Christina Y.
Gambel Phillip
Rush-Presbyterian-St. Luke's Medical Center
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