Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1984-07-12
1986-12-16
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 7, 514917, 514921, 424 88, 424 92, A61K 3702
Patent
active
046297227
ABSTRACT:
The present invention is directed to a method of inhibiting the onset of acute radiation syndrome caused by the exposure of warm-blooded animals to a whole body dose of at least about 100 rads of x-radiation. The invention is also directed to a method of inhibiting the onset of septicemia. The methods comprise administering to a warm-blooded animal an effective amount of a pharmaceutical composition comprising refined detoxified endotoxin in combination with a pharmaceutically acceptable carrier.
REFERENCES:
patent: 4436728 (1984-03-01), Rabi et al.
CA. No. 185374h, vol. 88, 1978, Relation between Four Types of Radiation Damage and Induced Repair, Radar.
Ziegler et al., Treatment of Gram-Negative Bacteremia and Shock . . . E. coli, Zama, vol. 307(20) 1982, p. 1225.
CA. No. 956n, vol. 87, 1977, Experimental Septic Shock, Hinshaw et al.
CA. No. 86685(q), vol. 97, 1982, Effect of Pretreatment . . . Dogs, Balogh et al.
CA. No. 103796x, vol. 101, Prevention of . . . Shock . . . Endotoxin Pretreatment, Balogh.
CA. No. 204517s, vol. 100, Bacterial Endotoxins . . . Resistance, Larand.
Draper Garnette D.
Kight John
Ribi ImmunoChem Research Inc.
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