Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Peroxide or compositions of or releasing gaseous oxygen or...
Patent
1994-12-01
1997-01-07
Pak, John
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Peroxide or compositions of or releasing gaseous oxygen or...
424810, 514929, 422 24, 422 44, 422 45, 422 46, 604 4, 435 2, A01N 100, A61K 3300, A61L 210
Patent
active
055914578
ABSTRACT:
A method of inhibiting the aggregation of blood platelets in a human, which comprises: (a) contacting from about 0.01 ml to about 400 ml of blood with a blood platelet aggregation-inhibiting effective amount of ozone gas and ultraviolet radiation; and (b) administering the blood treated in step (a) to a human. A method of stimulating the immune system, and of treating immune system disorders, by treating blood with ultraviolet radiation and ozone gas, followed by administering the treated blood to a human.
Also disclosed is a method of treating Raynaud's Disease by contacting about 0.01 ml to about 400 ml of human blood with a blood platelet aggregation-inhibiting effective amount of ozone gas in admixture with oxygen gas, and ultraviolet radiation, while maintained at a temperature in the range of from about 37.degree. C. to about 43.degree. C. for a period for about 0.5 minutes to about 10 minutes, and administering the blood so treated to a human patient with Raynaud's Disease.
REFERENCES:
patent: 695657 (1902-03-01), Smith
patent: 3715430 (1973-02-01), Ryan
patent: 3925344 (1975-12-01), Mazur
patent: 4061736 (1977-12-01), Morris et al.
patent: 4473496 (1984-09-01), Scannon
patent: 4500534 (1985-02-01), Frehel et al.
patent: 4529719 (1985-07-01), Tye
patent: 4584130 (1986-04-01), Bucci et al.
patent: 4600531 (1986-07-01), Walder
patent: 4632980 (1990-06-01), Zee et al.
patent: 4659726 (1987-04-01), Yoshino et al.
patent: 4826811 (1989-05-01), Sehgal et al.
patent: 4831268 (1989-05-01), Fisch et al.
patent: 4857636 (1989-08-01), Hsia
patent: 4968483 (1990-11-01), Mueller et al.
patent: 4983637 (1991-01-01), Herman
patent: 5028588 (1991-07-01), Hoffman et al.
patent: 5052382 (1991-10-01), Wainwright
patent: 5194590 (1993-03-01), Sehgal et al.
patent: 5250665 (1993-10-01), Kluger et al.
Medline Abstract 91104111, abstracting: Petukhov, E. B. et al. "Correction of Blood Hyperviscosity . . . " Grud Seroechnososudistaia Khir, (1990) (10), pp. 34-37.
Medline Abstract 90020932, abstracting: Petukhov, E. B. et al. "Decreased Activity of Lipid . . . " Vestn Khir (May 1989), vol. 142(5), pp. 36-39.
Medline Abstract 80130497, abstracting: Vella Briffa D. et al. "Inhibition of human blood platelet aggregation . . . " Br. J. Dermatol. (1979 Dec.), vol. 101(6), pp. 679-683.
Drug Facts and Comparisons, 1994 edition, published by Facts and Comparisons, St. Louis, see pp. 263-269.
Cecil Textbook of Medicine, 19th ed., published by W. B. Saunders Co., PA, 1992, pp. 253-269, 823, 1085, 1530-1534 and 2161.
Physicians' Desk Reference, 47th ed., published by Medical Economics Data, NJ, 1993, pp. 710 and 2408-2411.
Rook, Alain H. et al., "Treatment of Autoimmune Disease with Extracorporeal Photochemotherapy: progressive systemic sclerosis," The Yale J. of Biology and Medicine, vol. 62, No. 6, Nov./Dec. 1989, pp. 639-645.
Tattoni, G. et al., "Osservazioni sull'efficacia di un trattamento balneoterapico ozonizzato in pazienti affetti da vasculopatie periferiche," Minerva Cardioangiologica, vol. 25/9, 1977, pp. 745-748.
"Cloned and Expressed Nitric Oxide Synthase Structurally Resembles Cytochrome P-450 Reductase," Nature, Jun. 27, 1992, vol. 351, pp. 714-718.
British Medical Journal, vol. 296, Jan. 30, 1988, pp. 320-331, entitled "Secondary Prevention of Vascular Disease by Prolonged Antiplatelet Treatment".
"Ozone: Historical Review," published in Biomedical Technology, Dec. 16, 1991, p. 5.
"Biological Roles of Nitric Oxide," Scientific American, May 1992, pp. 68-77.
D. Baran et al (associates) "Technical Report and Clinical Update" Mueller Medical International Inc., Oakville, Ontario, Canada, Sep. 1990.
Pak John
Vasogen Inc
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