Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Reexamination Certificate
2008-09-02
2008-09-02
Kishore, Gollamudi S (Department: 1612)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
C514S001000, C514S021800
Reexamination Certificate
active
09183375
ABSTRACT:
A method is provided for inhibiting or preventing toxicity and other unwanted effects (a) caused by solvents for pharmaceuticals which solvents or emulsifier which contain amphiphilic molecules such as polyethoxylated oils or a derivative thereof, or (b) caused by a drug in a vehicle containing amphiphilic molecules such as phopholipids or derivative thereof, emptying a complement inhibitor. Drug compositions containing amphiphilic molecules, or derivatives thereof and a complement inhibitor, and pharmaceutical compositions including a drug, solvent or carrier containing amphiphilic molecules or derivatives thereof, and a complement inhibitor are also provided.
REFERENCES:
patent: 5462726 (1995-10-01), Lodge
patent: 5478860 (1995-12-01), Wheeler et al.
patent: 5744156 (1998-04-01), De Lacharriere
patent: 5851528 (1998-12-01), Ko
patent: 5877396 (1999-03-01), Ravetch et al.
patent: 6495735 (2002-12-01), White et al.
patent: 0 584 001 (1994-02-01), None
patent: WO 97/26862 (1997-07-01), None
Decorti et al., 1996 “Effect of Paclitaxel and Cremophor EL on Mast Cell Histamine Secretion and Their Interaction with Adriamycin” Anticancer Research 16: 317-320.
Eisenhauer et al., 1994 “European-Canadian Randomized Trial of Paclitaxel in Relapsed Ovarian Cancer: High-Dose Versus Low-Dose and Long Versus Short Infusion” Journal of Clinical Oncology, 12(12): 2654-2666.
Essayan et al., 1996 “Successful Parenteral Desensitization to Paclitaxel” Journal of Allergy Clinical Immunology, 97(1): 42-46.
Hammerschmidt et al., 1980 “Association of Complement Activation and Elevated Plasma-C5a With Adult Respiratory Distress Syndrome” The Lancet, May 3, 1980: 947-949.
Marceau et al., 1987 “Effects of the Anaphylatoxins on Circulation” Immunopharmacology, 14: 67-84.
Michaud, 1997 “Methods for Preventing Reactions Secondary to Cremophor EL” Annals of Pharmacotherapy, 31(11): 1402-1404.
O'Brien et al., 1992 “Allergic Reactions to Cytotoxic Drugs—an Update” Annals of Oncology, 3: 605-610.
Szebeni, 1998 “The Interaction of Liposomes with the Complement System” Critical Reviews in Therapeutic Drug Carrier Systems, 15(1): 57-88.
Szebeni et al, 1998 “Complement Activation by Cremophor EL as a Possible Contributor to Hypersensitivity to Paclitaxel: an In Vitro Study” Journal of the National Cancer Institute, 90(4): 300-306.
Szebeni et al., 1997 “Complement Activation In Vitro by the Red Cell Substitute, Liposome-encapsulated Hemoglobin: Mechanism of Activation and Inhibition by Soluble Complement Receptor Type 1” Transfusion, 37(2): 150-159.
Szebeni et al., 1997) “Complement Activation and Thromboxane Secretion by Liposome-Encapsulated Hemoglobin in Rats In Vitro: Inhibition by Soluble Complement Receptor Type 1” Art., Cells, Blood Subs., and Immob. Biotech., 25(4): 347-355.
Terwogt et al, 1997 “Alternative Formulations of Paclitaxel” Cancer Treatment Reviews 23(2): 87-95.
Wassef et al., 1989 “Anaphylactoid Reactions Mediated by Autoantibodies to Cholesterol in Miniature Pigs” The Journal of Immunology 143(8): 2990-2995.
Weiss et al., 1990 “Hypersensitivity Reactions From Taxol” Journal of Clinical Oncology, 8(7): 1263-1268.
Alving Carl R.
Szebeni Janos
Arwine Elizabeth
Harris Charles H.
Kishore Gollamudi S
United States of America as Represented by the Secretary of the
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