Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1987-03-16
1990-09-25
Griffin, Ronald W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 25, 514 26, 514411, 514731, 514733, 514870, 536 41, 536 5, 536 44, A61K 3105, A61K 3140, A61K 31705, A61K 3170
Patent
active
049593552
ABSTRACT:
This invention provides a method of inhibiting osmotic water flow across mammalian cell membranes which involves contacting the water channels of the cell membranes with an effective amount of a glucose transport blocker or of digitonin so as to inhibit osmotic water flow across the membranes.
Additionally, this invention provides a method of treating a subject afflicted with a condition associated with abnormal osmotic water flow across cell membranes which comprises administering to the subject an effective amount of a glucose transport blocker or of digitonin so as to contact the water channels of the subject's cell membranes and inhibit osmotic water flow across the membranes.
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Fischbarg Jorge
Koniarek Jan P.
Liebovitch Larry S.
Carson Nancy S.
Griffin Ronald W.
The Trustees of Columbia University in the City of New York
White John P.
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