Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1992-02-28
1993-09-21
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
514866, A61K 31155
Patent
active
052469719
ABSTRACT:
A method is disclosed for inhibiting nitric oxide formation in a warm blooded mammal which comprises administering to said mammal an effective nitric oxide inhibitory amount of methylguanidine or dimethylguanidine.
REFERENCES:
patent: 4758583 (1988-07-01), Cerami et al.
patent: 4983604 (1991-01-01), Ulrich et al.
Bredt et al., Nature 351, 714-718 (1991).
Moncada et al., Pharmacol. Rev. 43, 109-142 (1991).
Brownlee et al., Science 232, 1629-1632 (1986).
Bucala et al, J. Clin, Invest. 87, 432.gtoreq.438 (1991).
Tilton et al. Invest. Ophthalmol. Vis. Sci. 31, 342 (1990).
Wiliamson et al., Diabetes & Metabolisme 16, 369-370 (1990).
Chang et al., Diabetes 40 (Supp. 1) 210A (1991).
Corbett et al., J. Biol. Chem. 266, 21351-21354 (1991).
Chem. Absts. 115: 248104, Griffith WO 91 04,023 (1991).
Corbett John A.
McDaniel Michael L.
Tilton Ronald G.
Williamson Joseph R.
Henley III Raymond J.
Meyer Scott J.
Waddell Frederick E.
Washington University
LandOfFree
Method of inhibiting nitric oxide formation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of inhibiting nitric oxide formation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of inhibiting nitric oxide formation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1050265