Method of inhibiting myocardial ischemia in mammals using quater

Details Method of inhibiting myocardial ischemia in mammals using quater Method of inhibiting myocardial ischemia in mammals using quater

1976-08-19

1977-09-13

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424199, A61K 3114, A61K 31685

Patent

active

040483355

ABSTRACT:
1-(N-isopropyl-N,N-dimethylamino)-3-(1-naphthoxy)propan-2-ol quaternary salts are useful cardiovascular agents as evidenced by their potent and long-acting anti-arrhythmic, anti-fibrillatory and myocardial ischemia-inhibitory activity. They, furthermore, lack the undesirable side-effects, e.g. .beta.-adrenergic receptor blocking and local anesthetic activity, characteristic of related prior art compounds.

REFERENCES:
patent: 3452102 (1969-06-01), Lednicer
patent: 3658815 (1972-04-01), Fouche

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