Method of inhibiting hyperglycemia and pharmaceutical compositio

Details Method of inhibiting hyperglycemia and pharmaceutical compositio Method of inhibiting hyperglycemia and pharmaceutical compositio

1995-06-20

1998-01-27

Mullis, Jeffrey C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A01N 4350

Patent

active

057122830

ABSTRACT:
A method of using moxonidine or a physiologically acceptable acid addition salt thereof for the treatment and/or prophylaxis of hyperglycaemia, and pharmaceutical compositions for use therein.

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Mueller et al., "Steady State Investigation of Possible Pharmokinetic Interactions of Moxonidine and Glibenclamide" European Journal of Drug Metabolism and Pharmokinetics, 1993, vol. 18, No. 3, pp. 277-283.
Abstract of Published German Patent Application No. DE 2,849,537, Mar. 17, 1983 Derwent.
Schwarz et al., "Langzeiterfahrungen mit Moxonidin, einem neuen Antihypertensivum" (Long-Term Experience with Moxonidine, a new Anti-hypertensive Drug), Fortschr. Med., 108:(32) 616-20 (1990).
Trieb et al., "Wirksamkeit und Vertraeglichkeit des Imidazol-Rezeptor-Agonisten" (Effectiveness and Compatibility of the Imidazole Receptor Against), Medwelt, 45:440-45 (1994).
Rupp et al., "Modification of Myosin Isozymes and SR Ca.sup.2+ pump ATPase of the Diabetic Rat . . . ", Molecular and Cellular Biology, 132:69-80 (1994).
Michel et al., "From .alpha..sub.2 -Adrenoceptors to Imidazoline Receptors: Putative Progress for Cardiovasular Therapy", Journal of Cardiovascular Pharmacology, 20 (Suppl. 4):S24-S30 (1992).
Rupp et al., Therapiewoche, vol. 43, Nos. 32/33, pp. 1686-1693 (1993).
Dotzer et al., Z. Allg. Med., 68:760-763 (1992).

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