Method of inhibiting human G-protein chemokine receptor...

Details Method of inhibiting human G-protein chemokine receptor... Method of inhibiting human G-protein chemokine receptor...

2011-01-04

2011-01-04

Kolker, Daniel E (Department: 1649)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C424S142100, C424S133100, C424S139100, C424S085200, C424S116000, C424S184100, C424S278100, C514S001000

Reexamination Certificate

active

07862818

ABSTRACT:
The present invention relates to a novel human protein called Human G-protein Chemokine Receptor (CCR5) HDGNR10, and isolated polynucleotides encoding this protein. The invention is also directed to human antibodies that bind Human G-protein Chemokine Receptor (CCR5) HDGNR10 and to polynucleotides encoding those antibodies. Also provided are vectors, host cells, antibodies, and recombinant methods for producing Human G-protein Chemokine Receptor (CCR5) HDGNR10 and human anti-Human G-protein Chemokine Receptor (CCR5) HDGNR10 antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to this novel human protein and these novel human antibodies.

REFERENCES:
patent: 4988710 (1991-01-01), Olney
patent: 5030576 (1991-07-01), Dull et al.
patent: 5034400 (1991-07-01), Olney
patent: 5071964 (1991-12-01), Dustin et al.
patent: 5089603 (1992-02-01), Chang et al.
patent: 5110906 (1992-05-01), Maddon et al.
patent: 5132403 (1992-07-01), Kishimoto
patent: 5155027 (1992-10-01), Sledziewski et al.
patent: 5169941 (1992-12-01), Mach et al.
patent: 5198359 (1993-03-01), Taniguchi et al.
patent: 5314992 (1994-05-01), Guyre et al.
patent: 5359046 (1994-10-01), Capon et al.
patent: 5367057 (1994-11-01), Lemischka
patent: 5440021 (1995-08-01), Chuntharapai et al.
patent: 5652133 (1997-07-01), Murphy
patent: 5707815 (1998-01-01), Charo et al.
patent: 5776729 (1998-07-01), Soppet et al.
patent: 5798206 (1998-08-01), Neurath et al.
patent: 5817310 (1998-10-01), Ramakrishnan et al.
patent: 5912176 (1999-06-01), Wang
patent: 5919776 (1999-07-01), Hagmann et al.
patent: 5928881 (1999-07-01), Barnette et al.
patent: 5939320 (1999-08-01), Littman et al.
patent: 5939538 (1999-08-01), Leavitt et al.
patent: 5961976 (1999-10-01), Wang
patent: 5962462 (1999-10-01), Mills et al.
patent: 5994515 (1999-11-01), Hoxie
patent: 6013644 (2000-01-01), Mills et al.
patent: 6025154 (2000-02-01), Li et al.
patent: 6057102 (2000-05-01), Landau et al.
patent: 6075181 (2000-06-01), Kucherlapati et al.
patent: 6107019 (2000-08-01), Allaway et al.
patent: 6132987 (2000-10-01), Charo et al.
patent: 6150584 (2000-11-01), Kucherlapati et al.
patent: 6153431 (2000-11-01), Beretta et al.
patent: 6258527 (2001-07-01), Littman et al.
patent: 6265184 (2001-07-01), Gray et al.
patent: 6268477 (2001-07-01), Gray et al.
patent: 6287805 (2001-09-01), Graham et al.
patent: 6344545 (2002-02-01), Allaway et al.
patent: 6448375 (2002-09-01), Samson et al.
patent: 6511826 (2003-01-01), Li et al.
patent: 6528625 (2003-03-01), Wu et al.
patent: 6692938 (2004-02-01), Samson et al.
patent: 6743594 (2004-06-01), Li et al.
patent: 6759519 (2004-07-01), Li et al.
patent: 6797811 (2004-09-01), Gray et al.
patent: 6800447 (2004-10-01), Samson et al.
patent: 6800729 (2004-10-01), Li et al.
patent: 7160546 (2007-01-01), Li et al.
patent: 7175988 (2007-02-01), Roschke et al.
patent: 7393934 (2008-07-01), Roschke et al.
patent: 2003/0003440 (2003-01-01), Lopalco
patent: 2004/0087552 (2004-05-01), Hale et al.
patent: 2007/0122405 (2007-05-01), Roschke et al.
patent: 2008/0241124 (2008-10-01), Li et al.
patent: 2146328 (1994-05-01), None
patent: 2128208 (1994-06-01), None
patent: 0 612 723 (1994-08-01), None
patent: 0 671 391 (1995-09-01), None
patent: 0 834 564 (1998-05-01), None
patent: 0 945 464 (1999-09-01), None
patent: 0 979 655 (2000-02-01), None
patent: 2 771 423 (1999-05-01), None
patent: 10-179180 (1998-07-01), None
patent: 11-243960 (1999-09-01), None
patent: 11-292795 (1999-10-01), None
patent: 2126048 (1999-02-01), None
patent: WO 92/01810 (1992-02-01), None
patent: WO-92/11018 (1992-07-01), None
patent: WO 94/11504 (1994-05-01), None
patent: WO 95/19436 (1995-07-01), None
patent: WO 96/22371 (1996-07-01), None
patent: WO 96/23068 (1996-08-01), None
patent: WO 96/38559 (1996-12-01), None
patent: WO 96/39437 (1996-12-01), None
patent: WO 97/00960 (1997-01-01), None
patent: WO-97/13844 (1997-04-01), None
patent: WO 97/19696 (1997-06-01), None
patent: WO 97/21812 (1997-06-01), None
patent: WO 97/22698 (1997-06-01), None
patent: WO 97/25340 (1997-07-01), None
patent: WO 97/28258 (1997-08-01), None
patent: WO 97/32019 (1997-09-01), None
patent: WO 97/35881 (1997-10-01), None
patent: WO 97/37005 (1997-10-01), None
patent: WO 97/41225 (1997-11-01), None
patent: WO 97/41230 (1997-11-01), None
patent: WO 97/44055 (1997-11-01), None
patent: WO 97/45543 (1997-12-01), None
patent: WO 97/46697 (1997-12-01), None
patent: WO 97/47318 (1997-12-01), None
patent: WO 97/47319 (1997-12-01), None
patent: WO 97/49424 (1997-12-01), None
patent: WO 98/00535 (1998-01-01), None
patent: WO 98/02151 (1998-01-01), None
patent: WO 98/05798 (1998-02-01), None
patent: WO 98/11218 (1998-03-01), None
patent: WO 98/14480 (1998-04-01), None
patent: WO 98/15569 (1998-04-01), None
patent: WO 98/17308 (1998-04-01), None
patent: WO 98/18826 (1998-05-01), None
patent: WO 98/20166 (1998-05-01), None
patent: WO 98/25604 (1998-06-01), None
patent: WO 98/25605 (1998-06-01), None
patent: WO 98/25617 (1998-06-01), None
patent: WO 98/27815 (1998-07-01), None
patent: WO 98/30218 (1998-07-01), None
patent: WO 98/31364 (1998-07-01), None
patent: WO 98/34945 (1998-08-01), None
patent: WO 98/38212 (1998-09-01), None
patent: WO 98/42354 (1998-10-01), None
patent: WO 98/44158 (1998-10-01), None
patent: WO 98/51705 (1998-11-01), None
patent: WO 98/54317 (1998-12-01), None
patent: WO 98/55873 (1998-12-01), None
patent: WO 98/56421 (1998-12-01), None
patent: WO 98/58536 (1998-12-01), None
patent: WO 98/58966 (1998-12-01), None
patent: WO 99/01127 (1999-01-01), None
patent: WO 99/04794 (1999-02-01), None
patent: WO 99/06561 (1999-02-01), None
patent: WO 99/08703 (1999-02-01), None
patent: WO 99/09984 (1999-03-01), None
patent: WO 99/12416 (1999-03-01), None
patent: WO 99/13112 (1999-03-01), None
patent: WO 99/14378 (1999-03-01), None
patent: WO 99/17773 (1999-04-01), None
patent: WO 99/23107 (1999-05-01), None
patent: WO 99/23253 (1999-05-01), None
patent: WO 99/24065 (1999-05-01), None
patent: WO 99/24553 (1999-05-01), None
patent: WO 99/27122 (1999-06-01), None
patent: WO 99/27939 (1999-06-01), None
patent: WO 99/28474 (1999-06-01), None
patent: WO 99/32100 (1999-07-01), None
patent: WO 99/32138 (1999-07-01), None
patent: WO 99/33989 (1999-07-01), None
patent: WO 99/36518 (1999-07-01), None
patent: WO 99/38514 (1999-08-01), None
patent: WO 99/43711 (1999-09-01), None
patent: WO 99/46372 (1999-09-01), None
patent: WO 99/51751 (1999-10-01), None
patent: WO 99/53033 (1999-10-01), None
patent: WO 99/62535 (1999-12-01), None
patent: WO 99/66944 (1999-12-01), None
patent: WO 99/67429 (1999-12-01), None
patent: WO 00/02045 (2000-01-01), None
patent: WO 00/05265 (2000-02-01), None
patent: WO 00/06085 (2000-02-01), None
patent: WO 00/06146 (2000-02-01), None
patent: WO 00/06153 (2000-02-01), None
patent: WO 00/08043 (2000-02-01), None
patent: WO 00/09525 (2000-02-01), None
patent: WO 00/10965 (2000-03-01), None
patent: WO 00/14220 (2000-03-01), None
patent: WO 00/15663 (2000-03-01), None
patent: WO 00/15785 (2000-03-01), None
patent: WO 01/58915 (2001-08-01), None
patent: WO 01/58916 (2001-08-01), None
patent: WO 01/96388 (2001-12-01), None
patent: WO 02/064612 (2002-08-01), None
patent: WO-02/083172 (2002-10-01), None
patent: WO 02/083172 (2002-10-01), None
patent: WO-03/072766 (2003-09-01), None
patent: WO 03/075944 (2003-09-01), None
patent: WO 2004/020468 (2004-03-01), None
patent: WO-2005/105841 (2005-11-01), None
patent: WO-2007/014114 (2007-02-01), None
Chuntharapai A et al. Generation of monoclonal antibodies to chemokine receptors. Methods Enzymology, 1997; 288:15-27.
Oki M et al. Accumulation of CCR5+ T cells around RANTES+ granulomas in Crohn's disease: a pivotal site of Th1-shifted immune response? Lab Invest. Jan. 2005; 85(1):137-145.
Petrek M et al. CC chemokine receptor 5 (CCR5) mRNA expression in pulmonary sarcoidosis. Immunol Lett. Mar. 2002; 80(3):189-193.
Tokuyama H et al. THe simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist p

Affiliated with

Also associated with

Rating

Method of inhibiting human G-protein chemokine receptor... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of inhibiting human G-protein chemokine receptor..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of inhibiting human G-protein chemokine receptor... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2638575