Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-05-29
1989-01-03
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 12, 514885, 530370, 4241951, A61K 3702, A61K 3578, A61K 3580, C07G 700
Patent
active
047957395
ABSTRACT:
A method of inhibiting expression of HIV antigens in human blood cells infected with HIV. The infected cells are exposed to a plant protein or glycoprotein, such as trichosanthin or momorcharin, at a concentration sufficient to (a) produce a substantial reduction in the level of HIV antigen, and (b) effect a selective reduction in the number of HIV-infected cells, with respect to uninfected cells of the same type. The method is used to treat HIV infection in humans. In another aspect, the invention includes a method of screening drug agents effective in treating HIV infection in humans.
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Hwang Kou M.
Lifson Jeffrey D.
McGrath Michael S.
Yeung Hin-Wing
Dehlinger Peter J.
Gene Labs, Inc.
Kight John
Nutter Nathan M.
Regents of University of California
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