Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – C-o-group doai
Reexamination Certificate
2006-05-02
2006-05-02
Padmanbhan, Sreeni (Department: 1617)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
C-o-group doai
C514S734000, C514S736000
Reexamination Certificate
active
07037945
ABSTRACT:
The present invention provides a method of inhibiting the formation of pseudorabies particles in a host cell. The method involves administering an effective amount of a poly-hydroxylated stilbene, particularly resveratrol, to a herpes virus infected host cell. The present invention also provides a method of reducing or inhibiting the growth ofNeisseria gonorrheaandNeisseria meningiditisin vitro and in vivo. The method comprises administering a composition comprising a therapeutically effective amount of a tri-hydroxylated stilbene to a growth surface which has come into contact or could come into contact with the bacterium.
REFERENCES:
patent: 5500367 (1996-03-01), Hain et al.
patent: 6022901 (2000-02-01), Goodman
patent: 6197834 (2001-03-01), Docherty
Mahady et al, Am. J. of Gastroenterology, vol. 95, Jul. 2000, p. 1849.
Adesanya et al, 111CA:171177, 1989.
Lysko et al, 93CA:215955, 1980.
Anne, et al, 94CA:57949, 1980.
Miura et al. “Antioxidative and Prooxidative Action of Stilbene Derivatives” 2000, Pharmacology & Toxicology, 86, 203-208.
Pathan et al. “Pathophysiology of meningococcal meningitis and septicaemia” 2003, Arch Dis Child, 88, 601-607.
Zheng et al. “Antimicrobial susceptibility ofNeisseria gonorrhoeaestrains isolated in Guangzhou, China 1996-2001” 2003, Sex Transm Infect, 79, 399-402.
“Antibacterial Constituents ofFicus BarteriFruits” by Ogungbamila, et al.,International Journal of Pharmacognosy, vol. 35, No. 3, 1997, pp. 185-189.
“Resveretrol Inhibits the Growth ofHelicobacter pyloirin Vitro” by Mahady, et al.,American Journal of Gastroenterology, 95:1849, Jul. 2000.
“Resveretrol selectively inhibitsNeisseria gonorrhoeaeandNeisseria meningitidis” by Docherty, et al.,Journal of Antimicrobial Chemotherapy, 47:243-244, Feb., 2001.
“Oxidative Stress During Viral Infection: A Review” by Schwarz,Free Radical Biology&Medicine, vol. 21, No. 5, pp. 641-649, 1996.
“Effect of Stilbene Derivatives on Gastric H+, K+-ATPase” by Murakami, et al.,Biochemical Pharmacology, vol. 44, No. 10, pp. 1947-1951, 1992.
“Antioxidants Selectively Suppress Activation of NF-κB by Human T-Cell Leukemia Virus Type 1 Tax Protein” by Schreck, et al.,Journal of Virology, vol. 66, No. 11, Nov. 1992, pp. 6288-6293.
“Resveretrol Arrests the Cell Division Cycle at S/G2 Phase Transition” by Ragione, et al.,Biochemical and Biophysical Research Communication, 250, 53-58 (1998).
“Cancer Chemopreventive Activity of Resveretrol, a Natural Product Derived from Grapes” by Jang, et al.,Science, vol. 275, Jan. 10, 1997, pp. 218-220.
“Resveretrol: A Molecule Whose Time Has Come? And Gone?” by Soleas, et al.,Clinical Biochemistry, vol. 30, No. 2, Mar. 1997, pp. 91-113.
“Evaluation of antioxidant healing formulations in topical therapy of experimental cutaneous and genital herpes simplex viral infections” by Sheridan, et al.,Antiviral Research, 36 (1997) 157-166.
“Resveretrol, a remarkable inhibitor of ribonucleotide reductase” by Fontecave, et al.,FEBS Letters, 421 (1998) 277-279.
“Effect of diethylstilbestrol on replication and transformation by human herpes viruses” by Rapp, et al.,Intervirology(1979), 12(2), 103.
Calfee Halter & Griswold LLP
Mitchell Gregory W
Northeastern Ohio Universities College of Medicine
Padmanbhan Sreeni
LandOfFree
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