Drug – bio-affecting and body treating compositions – Chewing gum type
Patent
1979-04-23
1980-10-14
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Chewing gum type
127 29, 127 30, 424 52, 424180, 426 39, 426 74, 426658, 426660, 435184, 435193, A61K 968, A61K 718, A61K 3170
Patent
active
042281504
ABSTRACT:
Dextransucrase synthesis of dextran from sucrose is inhibited by novel fluorosucroses which are substituted with fluorine for at least the C.sub.6 hydroxyl, and which may also be substituted with fluorine for other hydroxyls. Oral compositions containing such fluorosucrose can be used to control dextran formation in the mouth. Dextran comprises the principal component of dental plaque.
REFERENCES:
patent: 2365776 (1944-12-01), Raymond et al.
patent: 2684961 (1954-07-01), Barham
patent: 2927058 (1960-03-01), Minto
Jung, Stephanie May, "Mechanistics Studies on the Dextran Sucrase of Streptococcus Sanguis ATCC 10558:Alpha 1-Fluoroglucose as a Substrate for the Enzyme", 273 p. (1977) from Diss. Abstr. Int. B (1978) 38(11):5337-5338, Univ. Microfilm into Order 7805862.
Jung S. M., Mayer R. M., Fed. Proc. (Fepra)36(3)(1977):931, "The Utilization of 1 Fluoroglucose as a Substitute for Dextran Sucrase".
Hough, L. et al., Nature London (1976):263(5580):800, "Enhancement in the Sweetness of Sucrose".
Robyt John F.
Zikopoulos John N.
Iowa State University & Research Foundation, Inc.
Rose Shep K.
LandOfFree
Method of inhibiting dextransucrase and oral compositions for us does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of inhibiting dextransucrase and oral compositions for us, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of inhibiting dextransucrase and oral compositions for us will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2100985