Method of inhibiting dextransucrase and oral compositions for us

Details Method of inhibiting dextransucrase and oral compositions for us Method of inhibiting dextransucrase and oral compositions for us

1980-08-06

1982-06-15

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Chewing gum type

424 49, 424180, 426 3, 426660, 536122, 536 11, 536 187, 536 55, A61K 716, A61K 968, A61K 3110, C07H 502

Patent

active

043351000

ABSTRACT:
Dextransucrase synthesis of dextran from sucrose is inhibited by substituted sucrose compounds which have an inhibiting group bonded to the 5-position ring carbon. Oral compositions containing such substituted sucrose compounds can be used to control dextran formation in the mouth, and dextran comprises the principal component of dental plaque.

REFERENCES:
patent: 2365776 (1944-12-01), Raymond et al.
patent: 2684961 (1954-07-01), Barham
patent: 2927058 (1960-03-01), Minto
patent: 4228150 (1980-10-01), Robyt et al.
Hough, L. et al., Nature, London (1976): 263(5580):800, "Enhancement in the Sweetness of Sucrose".
Drucker, D. B., J. Hum. Nutr., 1979 33(2), 114-124, Sweetening Agents in Food Drinks and Medicine Cariogenic Potential and Adverse Effects as Abstrin, Chem. Abstr. 91:3961D (1979).
Drucker, D. B., Arch. Oral. Biol., 1979, 24(12): 965-970, "Comparative Effects of the Substance Sweeteners Glucose Sorbitol Sucrose Xylitol and Trichlorosucrose on Lowering of pH by Two Oral S. Mutans Strains in Vitro", As Abstr. in Chem. Abstr. 93#8921q, 1980.
Jung Diss. Abstr. Int. B (1978), Alpha 1-Fluoroglucose as a Substrate for Dextran Sucrase.
Jung et al., Fed. Proc. 36(3) (1977):931, The Utilization of 1 Fluoro Glucose as a Substitute for Dextran Sucrase.
Anisuzzaman, et al., (1978), Carbohyd. Res. 61: 511-518.
Avigad, et al., (1956), Biochim, Biophys. Acta 20: 129-134.
Binkley, et al. (1979); Carbohyd. Res. 74: 337-340.
Bolton, et al. (1972), Carbohyd. Res. 21: 133-143.
Ganem, Bruce (1974), Tetrahedron Letters 1974 (11): 917-920.
Gibbons, et al. (1967), Arch. Oral Biol. 12: 11-24.
Gibbons, et al. (1968), Arch. Oral Biol. 13: 1249-1262.
Gibbons, et al. (1969), J. Bacteriol. 98: 341-346.
Khan, et al. (1980), Carbohyd. Res. 78: 185-189.
Lindley, et al. (1975), Carbohyd. Res. 43: 360-365.
Robyt, et al. (1974), Arch. Biochem. Biophys. 165: 634-640.
Scherp, Henry W. (1971), Science 173: 1199-1205.
Takeo, et al. (1974), Die Starke 26: 111-118.

Affiliated with

Also associated with

Rating

Method of inhibiting dextransucrase and oral compositions for us does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of inhibiting dextransucrase and oral compositions for us, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of inhibiting dextransucrase and oral compositions for us will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1919005