Method of inhibiting cell growth with the P.sub.2U receptor

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 691, 4353201, 435325, 435352, 435363, 536 235, C12Q 100, C12N 1512

Patent

active

056911564

ABSTRACT:
Isolated DNAs encoding the human P.sub.2U receptor are disclosed, along with vectors and host cells containing the same and methods of using the same. Host cells which are essentially free of endogenous P.sub.2U receptor expression, and which express a heterologous P.sub.2U receptor such as a murine P.sub.2U receptor, are also disclosed, along with methods of using the same.

REFERENCES:
patent: 4501729 (1985-02-01), Boucher et al.
patent: 5240846 (1993-08-01), Collins et al.
K.D. Lustic et al., Expression cloning of an ATP receptor from mouse neuroblastoma cells, Proc. Natl. Acad. Sci. 90, 5113-5117 (1993).
C. S. Stock, Breathing Easier: A Promising Treatment for Cystic Fibrosis, In: Endeavors: Research and Graduate Education at the University of North Carolina at Chapel Hill, 10, pp. 10-11 (Fall 1992).
H. Brown et al., Evidence that UTP and ATP Regulate Phospholipase C Through a Common Extracellular 5'-Nucleotide Receptor in Human Airway Epithelial Cells, Mol. Pharmacol. 40:648-655 (1991).
P. Murphy et al., Characterization of Phagocyte P2 Nucleotide Receptors Expressed in Xenopus Oocytes, J. Biol. Chem. 265:11615-11621 (1990).
Y. Masu et al., cDNA Cloning of Bovine Substance-K Receptor Through Oocyte Expression System, Nature, 329:836-838 (1987).
G. Wahl et al., Screening Colonies or Plaques with Radioactive Nucleic Acid Probes, Methods in Enzymology, 152:415-422 (1987).
Y. Harada et al., Expresion of Two Different Tachykinin Receptors in Xenopus Oocytes by Exogenous mRNAs, J. of Neurosci., 7:3265-3273 (1987).
Vandewalle et al., Cancer Letters, vol. 85, 47-54, 1994.
Popper et al., Cell Calcium, vol. 14, 209-18, 1993.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of inhibiting cell growth with the P.sub.2U receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of inhibiting cell growth with the P.sub.2U receptor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of inhibiting cell growth with the P.sub.2U receptor will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2105917

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.