Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1997-04-11
1998-05-19
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 89, 514 91, A61K 31675
Patent
active
057536333
ABSTRACT:
A method is disclosed for inhibiting bone resorption, concomitant with the overproduction of PTH associated with hyperparathyroidism or secondary hyperparathyroidism, by providing a azacycloalkane-2,2-diphosphonic compound.
REFERENCES:
patent: 3941772 (1976-03-01), Ploger et al.
patent: 3988443 (1976-10-01), Ploger et al.
Journal of Bone and Mineral Research; vol. 6, No. 10, 1991, pp. 1037-1942; "Effects of Potassium Peroxydiphosphate on Bone Resorption".
Bone 8, Supp. 1, S23-S28 (1987); "Bisphosphonates--History and Experimental Basis", H. Fleisch.
"Effect of Phosphate, Calcium and Magnesium on Bone Resorption and Hormonal Responses in Tissue Culture", Raisz and Niemann, Departments of Pharmacology and Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, Sep. 1969 pp. 446-452.
Colgate-Palmolive Company
Goldberg Jerome D.
Goldfine Henry S.
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