Method of inhibiting blood clotting with desulfatohirudins

Details Method of inhibiting blood clotting with desulfatohirudins Method of inhibiting blood clotting with desulfatohirudins

1988-01-19

1989-01-31

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514822, 435 2, A01N 102, A61K 3702

Patent

active

048015768

ABSTRACT:
The present invention relates to desulfatohirudins, to the preparation thereof, to pharmaceutical compositions containing these compounds, and to the use thereof. The desulfatohirudins of this invention correspond to hirudin in biological activity and are therefore particularly useful for inhibiting blood clotting.

REFERENCES:
patent: 4654302 (1987-03-01), Fritz et al.
patent: 4668662 (1987-04-01), Tripier
patent: 4745177 (1988-05-01), Fritz et al.

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