Method of inhibiting angiogenesis of tumors

Details Method of inhibiting angiogenesis of tumors Method of inhibiting angiogenesis of tumors

1990-01-12

1993-03-09

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514 21, 530380, 530381, 530395, A61K 3702, C07K 1506, C07K 1514

Patent

active

051927446

ABSTRACT:
A method of inhibiting angiogenesis and preparations for use therein are disclosed. The preparations comprise human thrombospondin in trimer or monomer form or a fragment thereof capable of inhibiting vascularization. The method and preparations are especially applicable to the treatment of solid tumors including skin cancers for controlling tumor neovascularization and thereby arresting tumor enlargement.

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