Method of inhibiting amyloid protein aggregation and imaging...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S658000, C514S237800, C514S255020, C514S307000, C514S331000, C514S281000, C514S396000, C514S406000, C514S427000, C564S435000, C564S457000, C548S254000, C548S340100, C548S335500, C548S566000, C548S375100, C544S059000, C544S162000, C544S399000, C544S402000, C546S147000, C546S229000

Reexamination Certificate

active

06972287

ABSTRACT:
The present invention provides a method of treating Alzheimer's disease using a compound of Formula (I). Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of the Formula (I) and a method of imaging amyloid deposits, as well as new compounds of Formula (I).

REFERENCES:
patent: 5739169 (1998-04-01), Ocain et al.
patent: 0459136 (1991-12-01), None
patent: 0076969 (2000-12-01), None
Bowman et al. {Journal of the Chemical Society, Perkin Transactions 1: Organic and Bioorganic Chemistry (1972-1999) (1973), (1), 1-4}.
PCT International Search Report, PCT/US00/15071.
Höppener et al., “The Role of Islet Amyloid Polypeptide (IAPP)/Amylin in the Pathogenesis of Type 2 diabetes Mellitus: Implications From a Transgenic Mouse Study”,European Journal of Endocrinology, vol. 130, No. Suppl. 2, 1994, p. 63.
Höppener et al., “Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model”,Diabetologia, vol. 42, No. 4, 1999, pp. 427-434.
Cooper et al., “Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients”,Proc. Natl. Acad. Sci. USA, vol. 84, No. 23, 1997, pp. 8628-8632.
Cleaveland et al., “Site of Action of Two Novel Pyrimidine Biosynthesis Inhibitors Accurately Predicted by the Compare Program”,Biochemical Pharmacology, vol. 49, No. 7, 1995, pp. 947-954.
Sturm et al., “Elektrochemische Oxidation von Acridanen”,Chem. Ber., vol. 111, No. 1, 1978, pp. 227-239.

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