Method of inhibiting aldose reductase in diabetic hosts using ph

Details Method of inhibiting aldose reductase in diabetic hosts using ph Method of inhibiting aldose reductase in diabetic hosts using ph

1991-06-12

1993-04-13

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514731, 514866, A01N 3710, A01N 3108

Patent

active

052023559

ABSTRACT:
The use of alkyl or alkenyl phenols or pharmaceutical acceptable salts thereof as aldose reductase inhibitors, and hence, as an agent for preventing or alleviating chronic diabetic complications.

REFERENCES:
patent: 4185116 (1980-01-01), Barnish
patent: 4423075 (1983-12-01), Dvornik
Yasuda et al "Effect of . . . " Diabetes vol. 38; 832-838, Jul. 1989.
Itokawa et al "A Quantitative . . . " Chem. Abs. 111:166773q Nov. 6, 1989.
I. Kubo, et al., "Mulluscicides from the Cashew Anacardium occidentale and Their Large-Scale Isolation," J. Agric. Food Chem. 1986, 34, 970-973.
I. Kubo, et al., "Prostaglandin Synthetase Inhibitors from the African Medicinal Plant Ozoroa mucronate," Chem. Letters, 1987, 1101.

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