Method of inducing skeletal muscle relaxation

Details Method of inducing skeletal muscle relaxation Method of inducing skeletal muscle relaxation

1975-06-30

1977-12-27

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3144

Patent

active

040655610

ABSTRACT:
This invention relates to a method for inducing skeletal muscle relaxation in mammals suffering from pathological states that are characterized by hyperactivity of the spinal reflex arc, such as, for example, painful muscle spasm or spasticity, which comprises the administration to such a mammal of a non-toxic pharmaceutically effective amount of 1-methyl-2-(3-pyridyl) pyrrole or 1,5-dimethyl-2-(3-pyridyl) pyrrole.

REFERENCES:
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Larson, P. S. et al., Arch. Int. Pharmacodynamie, 83, 191-192, (1950).
Dingemanse et al., Arch. Exp. Path Pharmakol., 132365-381, (1928).
Oosterhuis et al., J. P. Rec. Trev. Chim. 55:729-736, (1936).
Kitamura, T., Fol. Pharm. Japan, (Brevearia), 54:825-837, (1958).
Clark et al. Arch Int. Pharmcodyne, 156:343-379, (1965).
Audier; A. G., Antonie Var Lecuivenhoch, 17:29-57, (1951).

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