Method of inducing diuresis with lysophospholipids

Details Method of inducing diuresis with lysophospholipids Method of inducing diuresis with lysophospholipids

1986-11-18

1988-05-24

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

A61K 31685

Patent

active

047466529

ABSTRACT:
Lysophospholipids are used to induce diuresis in a subject by administering them in a dose effective to increase the renal excretion of sodium. Exemplary compounds useful in this method include steroyl-lysophosphatidylcholine and steroyl-lysophosphatidylethanolamine.

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Tsukatani, H., Hypotensive Phospholipid Containing Choline is Obtained from Animal Tissue or Body Fluid (1978), (English Abstract and Foreign Language Document).
Vardaman M. Buckalew, Jr. and Kenneth A. Gruber, Ann. Rev. Physiol, 46, 343 (1984).
Vardaman M. Buckalew, Jr. and Kenneth A. Gruber, Natriuretic Hormone, in: The Kidney in Liver Disease (M. Epstein, 2nd Ed. 1983).

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