Method of inducing cellular differentiations and altering cell p

Details Method of inducing cellular differentiations and altering cell p Method of inducing cellular differentiations and altering cell p

1992-09-11

1994-11-29

Naff, David M.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352401, 514625, 514629, 544168, C12N 500, A61K 3116

Patent

active

053690303

ABSTRACT:
The present invention provides methods and pharmaceutical preparations of N-acyl-phenylaminoalcohol analogs for inducing differentiation of cells. Compositions having the formula ##STR1## wherein R.sub.1 is H, NO.sub.2, OH, chlorine, bromine or fluorine;

REFERENCES:
patent: 4816450 (1989-03-01), Bell
Abstract, Warren et al., 1976.
Bielawska et al., Ceramide-mediated . . . , 1992, 18493-18497.
Okzaki et al., Role of Ceramide . . . , 1990, pp. 15823-15831.
Merrill et al., Inhibition of Phorbol . . . , 1986, 12610-12615.
Jung Hyun et al., Synthetic Inhibitors . . . , 1975 vol. 166, pp. 382-389.
Wainer et al., Application of High . . . 259 (1983) 465-472.
Goodwin, B. J. et al. (1982) J. Clin. Invest. 70:699-706.
Arora, R. C. et al. (1972) Journal of Lipid Research 13:86-91.
Shapiro, D. et al. (1961) J. Am. Chem. Soc. 83:3327-3332.
Pick, Edgar et al. (1981) Immunol. Methods 46:211-226.
Hannun, Y. A. and Bell, R. M. (1989) Science 243:500-507.
Hannun, Y. A. et al. (1986) J. Biol Chem. 261:12604-12609.
Hannun, Y. A. and Bell, R. M. (1987) Science 235:670-674.
Hannun, Y. A. et al. (1987) J. Biol. Chem. 262:13620-13626.
Wilson, E. et al. (1987) Arch. Biochem. Biophys. 259:204-214.
Okazaki et al. (1990) J. Biol. Chem. 285:15823-15831.
Collins, S. J. (1987) Blood 70:1233-1244.
Okazaki et al (1989) J. Biol. Chem. 254:19076-19080.

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