Method of inducing antiandrogenic activity using imidazolidines

Details Method of inducing antiandrogenic activity using imidazolidines Method of inducing antiandrogenic activity using imidazolidines

1995-09-07

1997-07-08

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

5142358, 514252, 514256, 514278, 514314, 514326, 514361, 514362, 514363, 514365, 514374, 544 69, 544139, 544229, 544238, 544242, 544336, 546 13, 546 19, 546 20, 546193, 546210, C07D40104, C07D40304, A61K 31445, A61K 31415

Patent

active

056461720

ABSTRACT:
Novel imidazoles of the formula ##STR1## wherein the substituents are as defined in the disclosure and their non-toxic, pharmaceutically acceptable addition salts with acids and bases having antiandrogenic activity.

REFERENCES:
patent: 4320135 (1982-03-01), Kathawala
patent: 4944791 (1990-07-01), Schroder et al.
patent: 5221675 (1993-06-01), Chung et al.
Winters et al. (CA 73:98869) @1970.
Nakanishi et al. (CA 75:110315) @1971.
Nakanishi et al. (Derwent Abstract 44875S-B) Jul. 1971.
Sankyo (Derwent Abstract C90-104571), Sep. 1989.
Torigoshi, et al., "Spirohydantoin Derivatives", Chemical Abstracts, vol. 75, No. 17, Abstract No. 110315n, p. 437, 1971.
Winters, et al, "Synthesis of Spirohydantoins From Basic Heterocyclic Ketones", vol. 73, No. 19, Abstract No. 98869v, p. 368, 1970.
Nakanishi, et al, "Spirohydantoin Compounds", vol. 66, No. 15, Abstract No. 65473p, p. 6157, 1967.

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