Method of inducing a CTL response

Details Method of inducing a CTL response Method of inducing a CTL response

2006-02-07

2006-02-07

Chan, Christina (Department: 1644)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Animal or plant cell

C424S184100, C424S186100, C424S190100, C424S199100, C424S200100, C424S534000, C435S007230, C435S007240, C435S007920, C435S236000, C435S252000, C435S325000, C514S04400A, C530S300000, C530S350000, C530S351000, C536S023500

Reexamination Certificate

active

06994851

ABSTRACT:
A method of inducing a cytotoxic T-lymphocyte (CTL) response to an antigen is disclosed. The method involves delivering the antigen to the lymphatic system of an animal regularly over a sustained period of time using, e.g., an osmotic pump. The method is advantageous over prior art methods for inducing a CTL response in that it does not require repetitive immunizations or the use of adjuvants. The method of the present invention can be used for the induction of CTLs in tumor or infectious disease immunotherapy.

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