Method of indicating rheumatoid factors

Details Method of indicating rheumatoid factors Method of indicating rheumatoid factors

1977-07-25

1979-05-08

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

232306, 1951035A, 424 1, 424 8, 424 12, G01N 3316

Patent

active

041534174

ABSTRACT:
A method of indicating rheumatoid factors belonging to at least one of the immunoglobulin classes IgM, IgG and IgA in an aqueous sample is disclosed. According to this method any complement factor C1q present in the sample is pacified in a manner known per se, whereafter the sample is reacted with soluble, aggregated immunoglobulin labelled with one or more analytically indictable atoms or groups to form aggregates between rheumatoid factors and the aggregated, labelled immunoglobulin, said aggregate being precipitated out, whereafter the precipitate is separated and the analytically indicatable atoms or groups are indicated in the precipitation phase and/or in the solution.

REFERENCES:
patent: 3594466 (1971-07-01), Lille
patent: 3658982 (1972-04-01), Reiss
patent: 3689632 (1972-09-01), Mizushima
patent: 4062935 (1977-12-01), Masson
Chemical Abstracts, 71:58955x (1969).
Chemical Abstracts, 74:2303c (1971).

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