Method of increasing skin absorption of a drug

Details Method of increasing skin absorption of a drug Method of increasing skin absorption of a drug

1990-11-20

1993-03-23

Howell, Kyle L.

Surgery

Means for introducing or removing material from body for...

Infrared, visible light, ultraviolet, x-ray or electrical...

A61N 130

Patent

active

051959534

ABSTRACT:
A thin layer of a drug in a liquid form in a carrier is applied to the skin. Thereafter, 15-30 milliamps of a D.C. current is applied to the skin and drug by an iontophoresis device capable of being hand held and activated by thumb contact with a positive electrode and scalp skin contact with a negative electrode. The device has a two component housing enclosing an electrical circuit connecting the two electrodes. The circuit utilizes a 9 V battery, two load regulators, two capacitors, a momentary switch and a 2V-40V output range DC/DC converter. Alternatively, negative electrodes of varying structure can be plugged into the device to provide multi-purpose application to the scalp and the positive electrode can be separately plugged to the device to free the hand of the treating technician.

REFERENCES:
patent: 4292968 (1981-10-01), Ellis
patent: 4325367 (1982-04-01), Tapper
patent: 4419092 (1983-12-01), Jacobsen et al.
patent: 4722726 (1988-02-01), Sanderson et al.
patent: 4765310 (1988-08-01), Deagle et al.
patent: 5088977 (1992-02-01), Sibalis

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