Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1987-01-06
1989-11-28
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
424 852, 424 86, A61K 3942, A61K 39395, A61K 3516, A61K 3702
Patent
active
048836621
ABSTRACT:
An in vivo method is described for increasing the population of Natural Killer (NK) cells in the blood of patients suffering from cancer, such NK cells having known activity against tumor cells. The method broadly involves injecting a specially prepared biologic into the patient's bloodstream and allowing the biologic to activate the patient's immune system so as to achieve a desired NK cell population increase (preferably at least a twofold increase). The biologic is produced by injecting an animal such as a goat with a virus (preferably a normally immunosuppressive Parvovirus) and allowed to react to the virus for a period of time to generate the biologic in its blood serum; blood is then withdrawn from the animal and the serum fraction thereof, containing the desired biologic, can be used in fractionated or more highly purified form.
REFERENCES:
patent: 4572834 (1986-02-01), Stout
patent: 4687665 (1987-08-01), Stout
patent: 4689222 (1987-08-01), McMichael
patent: 4690915 (1987-09-01), Rosenberg
patent: 4692332 (1987-09-01), McMichael
Clinical Biotechnologies, Inc.
Rose Shep K.
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