Method of increasing egg production in avian species by active i

Details Method of increasing egg production in avian species by active i Method of increasing egg production in avian species by active i

1992-09-22

1996-09-17

Ziska, Suzanne E.

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

4241851, 4241981, 800DIG4, 800DIG5, C12N 1500, A61K 3900

Patent

active

055570330

ABSTRACT:
The present method of increasing egg production in laying turkey hens includes actively immunizing the hens with vasoactive intestinal peptide. The peptide is conjugated to a protein to induce an antibody response in the hens. The resulting antibodies tie up vasoactive intestinal peptide naturally produced in the turkey. This lack of naturally produced VIP in the turkey in turn prevents the secretion of the hormone prolactin from the pituitary gland of the hens to eliminate the onset of broody behavior. The hens are immunized prior to the laying season and subsequently boosted with immunizations approximately once per month during the laying season.

REFERENCES:
M. E. El Halawani et al., "Vasoactive intestinal peptide is a hypothalamic prolactin-releasing neuropeptide in the turkey (Meleagris gallopavi)," Gen. Comp. Endocrinol., 78, 66-73 (1990).
M. E. El Halawani et al., "Enhanced vasoactive intestinal peptide-induced prolactin secretion from anterior pituitary cell of incubating turkeys (Meleagris Galloparvo),"Gen. Comp. Endocrinol., 80, 138-145 (1990).
T. R. Knapp et al., "Gonadal steroid modulation of basal and vasoactive intestinal polypeptide-stimulated prolactin release by turkey anterior pituitary cells," Gen. Comp. Endocrinol., 72, 226-236 (1988).
R. W. Lea et al., "Passive immunization against chicken vasoactive intestinal polypeptide suppresses plasma prolactin and crop sac development in incubating ring doves," Hormones Behav., 25, 283-294 (1991).
L. J. Mauro et al., "Alterations in hypothalamic vasoactive intestinal peptide-like immunoreactivity are associated with reproduction and prolactin release in female turkey," Endocrinol., 125, 1795-1804 (1989).
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P. J. Sharp et al. "The Role of Hypothalamic Vasoactive Intestinal Polypeptide in the Maintenance of Prolactin Secretion in Incubating Bantam Hens: Observations Using Passive Immunization, Radio-immunoassay and Immunohistochemistry." Dec. 2, 1988, pp. 5-14.
L. J. Mauro et al. "Alterations in Hypothalamic Vasoactive Intestinal Peptide-like Immunoreactivity Are Associated with Reproduction and Prolactin Release in the Female Turkey," Apr. 27, 1989. pp. 1795-1804.
M. E. El Halawani et al. "Vasoactive Intestinal Peptide is a Hypothalamic Prolactin-Releasing Neuropeptide in the Turkey (Meleagris galloparo)."Jun. 29, 1989. pp. 66-73.
M. E. Halawani et al. "Ehanced Vasoactive Intestinal Peptide Induced Prolactin Secretion from Anterior Pituitary Cells of Incubating Turkeys (Melagris galloparo)." Oct. 23, 1989. pp. 138-145.
R. W. Lea et al. "Passive Immunization Against Chicken Vasoactive Intestinal Polypeptide Suppressed Plasma Prolactin and Crop Sae Development in Incubating Ring Doves." 1991. pp. 283-294.
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