Method of inactivation of viral blood contaminants using acridin

Details Method of inactivation of viral blood contaminants using acridin Method of inactivation of viral blood contaminants using acridin

1991-04-16

1994-08-30

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

514297, A01N 102

Patent

active

053427521

ABSTRACT:
A method is provided for inactivating viral and/or bacterial and/or parasitic contamination in cellular blood matter or blood plasma protein fractions, using radiation sensitizing chemical compounds and irradiation with, for example, UV radiation.

REFERENCES:
patent: 3333583 (1967-08-01), Bodell
patent: 4071412 (1978-01-01), Eisenberg
patent: 4268279 (1981-05-01), Shindo
patent: 4325715 (1982-04-01), Bowman
patent: 4409105 (1983-10-01), Hayashi
patent: 4684521 (1987-08-01), Edelson
patent: 4748120 (1988-05-01), Wiesehahn
patent: 4870018 (1989-09-01), Lehmann
patent: 4874690 (1989-10-01), Goodrich
patent: 4878891 (1989-11-01), Judy
patent: 4950665 (1990-08-01), Floyd
patent: 4973327 (1990-11-01), Goodrich
Lin, L. et al, Blood, 74:517-525 (1989).
Sun, I. et al, J Clin Microbiology 8:604-611 (1978).
Cryobiology, vol. 10, issued 1973, D. Pribor, "Studies with Dextran 40 in cryopreservation of blood", pp. 93-103, see entire article.
Acta Vet Scand, vol. 20, issued 1979, V. Myhrvoid, "Cryopreservation of sheep red blood cells", pp. 531-536, see entire article.
R. Acheson et al., "Acridines" published 1956 by Interscience Publishers, Inc. (N.Y.), pp. 339-361, see pp. 352-355.
Mutation Research, vol. 81, issued 1981, W. Firth et al., "Azido Analogs of Acridine: Photoaffinity Probes for Frameshift Mutagenesis in Salmonella typhimurium", pp. 295-309, see p. 299.
Vox Sang, vol. 26, issued 1974, K. Ganshirt et al., "A Five-bag system for washing fresh erythrocytes and their preservation", see p. 66.
Vox Sang, vol. 55, issued 1988, G. Espersen et al., "Irradiated Blood Platelet Concentrates Stored for Five Days--Evaluation by in vitro Tests", pp. 218-221, see abstract.
Pharm. Delt. Epistom. Eksosis, vol. 1, No. 2, issued 1971, J. Polak et al., "The Bactericidal and Fungicidal Activity of Some Quinolinium Compounds", pp. 27-33. See entire article.
Exp. Parasitol., vol. 31 issued 1972, C. Lantz et al., "Plasmodium berghei: Inhibited Incorporation of AMP-8-.sup.3 H into Nucleic Acids of Erthrocyte-Free Malarial Parasites by Acridines, Phenanthridines, and 8-Aminoquinolines", pp. 255-261, see p. 258.

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