Method of inactivation of viral and bacterial blood contaminants

Details Method of inactivation of viral and bacterial blood contaminants Method of inactivation of viral and bacterial blood contaminants

1995-06-07

1999-09-21

Weber, Jon P.

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

4351731, 4351733, A01N 102, C12N 1300

Patent

active

059552565

ABSTRACT:
Viral, bacterial and parasitic contaminants in blood and cell culture containing compositions are inactivated by adding a photosensitizer and a blocking agent to the composition and irradiating the resulting mixture with electromagnetic radiation. Blocking agents reduce photolysis of the photosensitizer by mechanisms not involving the quenching of reactive oxygen species. The blocking agents reduce photolysis which occurs by ring opening. Preferred photosensitizers are quinoline or quinolone.

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