Method of inactivating reproductive filterable pathogens

Details Method of inactivating reproductive filterable pathogens Method of inactivating reproductive filterable pathogens

1987-05-12

1989-03-21

Rosen, Sam

Chemistry: molecular biology and microbiology

Process of utilizing an enzyme or micro-organism to destroy...

Treating animal or plant material or micro-organism

435272, C07K 300

Patent

active

048142778

ABSTRACT:
A method of inactivating reproductive filterable pathogens in immunoglobulin-G-containing blood fractions to be applied therapeutically or prophylactically. In order to preserve full activity of the blood products and to completely inactivate pathogenic viruses, an aqueous solution of an immunoglobulin-G-containing fraction obtained from human blood is treated with neutral hydrolases at a temperature of 4.degree. to 50.degree. C. and at a pH of 5.5 to 9.5.

REFERENCES:
patent: 2065196 (1936-12-01), Parfentjev
patent: 4312949 (1982-01-01), Ahrens

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