Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge
Patent
1991-02-01
1992-03-24
Niebling, John
Chemistry: electrical and wave energy
Processes and products
Electrostatic field or electrical discharge
204299R, 356344, B01D 5702, B01D 6142
Patent
active
050985361
ABSTRACT:
A method and apparatus for improving signal to noise in an electropherogram acquired by electrophoresis. The migration time is remapped by binning the data with respect to migration time to improve signal to noise and peak resolution. The data points of the electropherogram are pooled into variable size bins, each corresponding to a number of time intervals. The sizes of the bins increase with migration time. To further improve signal to noise and peak resolution, the binned data is filtered by Fourier transformation. The present invention allows for accurate determinatiion of DNA sequences.
Beckman Instruments Inc.
Harder Paul R.
Koestner Caroline
Liu Wen
May William H.
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