Method of improving signal-to-noise for quantitation by mass...

Radiant energy – Ionic separation or analysis – Methods

Reexamination Certificate

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C250S281000, C250S288000, C702S023000

Reexamination Certificate

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08067728

ABSTRACT:
Selectivity of a measurement from a mass spectrometer is improved by selecting an extracted ion current window for the measurement after data acquisition. A plurality of mass spectra are acquired over a period of time. A first extracted ion current window is selected and from the plurality of mass spectra a first intensity as a function of time is calculated for an ion using the first extracted ion current window. A second extracted ion current window is selected and from the plurality of mass spectra a second intensity as a function of time is calculated for the ion using the second extracted ion current window. A first signal-to-noise ratio of the first intensity is compared with a second signal-to-noise ratio of the second intensity. If the second signal-to-noise ratio is greater than the first signal-to-noise ratio, the second intensity as a function of time is used for the measurement.

REFERENCES:
patent: 5939612 (1999-08-01), Wylie et al.
patent: 6940065 (2005-09-01), Graber et al.
patent: 7279679 (2007-10-01), Old et al.
patent: 7473892 (2009-01-01), Sano et al.
patent: 2001/0027382 (2001-10-01), Jarman et al.
patent: 2002/0024010 (2002-02-01), Hager et al.
patent: 2004/0181351 (2004-09-01), Thompson et al.
patent: 2005/0206363 (2005-09-01), Ho et al.
patent: 2005/0261838 (2005-11-01), Andreev et al.
patent: 2006/0255258 (2006-11-01), Wang et al.
patent: 2006/0284067 (2006-12-01), Senko et al.
patent: 2006/0284069 (2006-12-01), Le Blanc
patent: 2007/0023633 (2007-02-01), Wang et al.
patent: 2008/0015793 (2008-01-01), Ben-Menahem et al.
patent: 2008/0015821 (2008-01-01), Roushall
patent: 2008/0149821 (2008-06-01), Senko
patent: 2008/0234945 (2008-09-01), Walk et al.
patent: 2009/0166224 (2009-07-01), Yang et al.
patent: 2010/0136703 (2010-06-01), Purkayastha
patent: 2010/0163721 (2010-07-01), Graves et al.
patent: WO/94/09698 (1994-05-01), None
Gomez et al., “Solid-phase extraction followed by liquid chromatography-time-of-flight-mass spectrometry to evaluate pharmaceuticals in effluents. A pilot monitoring study”, Journal of Environmental Monitoring, 2007, 9, pp. 718-729.
Borges et al. “Analysis of a Challenging Subset of World Anti-Doping Agency-Banned Steroids and Antiestrogens by LC-MS-MS” Journal of Analytical Toxicology, vol. 31, Apr. 2007, pp. 125-131.

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