Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1991-03-18
1992-11-03
Stoll, Robert L.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
5303888, 530808, 530809, 5303913, 530866, 424 858, 436501, 436548, 436808, 436813, 43524027, 935 95, 935103, 935106, 935110, A61K 4902, C07K 1528, C07K 1500
Patent
active
051607239
ABSTRACT:
This invention provides a method of imaging a colorectal carcinoma lesion in a human patient which comprises administering to the patient a monoclonal antibody capable of binding to a cell surface antigen associated with the coloretal carcinoma lesion and which is labeled with an imaging agent under conditions so as to form a complex between the monoclonal antibody and the cell surface antigen, imaging any complex so formed, and thereby imaging the colorectal carcinoma lesion.
This invention also provides a monoclonal antibody designated AS 33 (ATCC Accession No. HB 8779) and the hybridoma which produces it.
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Divgi Chaitanya R.
Oettgen Herbert F.
Old Lloyd J.
Real Francisco X.
Sakamoto Jun-ichi
Covert John M.
Sloan-Kettering Institute for Cancer Research
Stoll Robert L.
White John P.
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