Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Reexamination Certificate
2008-04-15
2008-04-15
Yaen, Christopher H. (Department: 1643)
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
C424S001110, C424S009100, C436S504000, C436S544000, C436S545000, C436S057000, C436S058000
Reexamination Certificate
active
07357915
ABSTRACT:
A method of imaging apoptosis in vivo, using radiolabeled annexin, is described.
REFERENCES:
patent: 4671256 (1987-06-01), Lemelson
patent: 5519221 (1996-05-01), Weinberg
patent: 5552525 (1996-09-01), Dean
patent: 5627036 (1997-05-01), Reutelingsperger
patent: 5632986 (1997-05-01), Tait et al.
patent: 5776427 (1998-07-01), Thorpe et al.
patent: 5855866 (1999-01-01), Thorpe et al.
patent: 5863538 (1999-01-01), Thorpe et al.
patent: 5955437 (1999-09-01), Reutelingsperger
patent: 5965132 (1999-10-01), Thorpe et al.
patent: 5968477 (1999-10-01), Kasina et al.
patent: 6004554 (1999-12-01), Thorpe et al.
patent: 6051230 (2000-04-01), Thorpe et al.
patent: 6261535 (2001-07-01), Thorpe et al.
patent: 6312694 (2001-11-01), Thorpe et al.
patent: 6406693 (2002-06-01), Thorpe et al.
patent: WO 92/19279 (1992-11-01), None
patent: WO 94/10149 (1994-05-01), None
patent: WO 95/27903 (1995-10-01), None
patent: WO 95/34315 (1995-12-01), None
patent: WO 95/34315 (1995-12-01), None
patent: WO 96/17618 (1996-06-01), None
patent: WO 98/04294 (1998-02-01), None
patent: WO 98/04294 (1998-02-01), None
patent: WO 00/02584 (2000-01-01), None
patent: WO 00/02584 (2000-01-01), None
patent: WO 00/02587 (2000-01-01), None
Delpassand et al J. Pharm. Sci. 1996; 85(6):553-559.
Ravanat C. et al Biochem J. Feb. 15, 1992;282 ( Pt 1):7-13.
Liu et al (Bioconjugate Chem 1996; 7:63-71).
Edwards et al (Bioconjugate Chem 1997;8:146-154).
Goodman et al (The Pharmacological Basis of Therapeutics; 1980, Macmillan Publishing Co.,Inc. pp. 1-27).
Shih et al (Clin Nucl Med. Nov. 1993;18(11):945-9).
Blankenberg et al. “Increased localization of TC-99m hydrazino nicotinamide (HYNIC) labeled annexin V lipocortin in lymphatic tissue of animals treated with dexamethazone.”J. Nuc. Med.1997;38(5):268P.
Blankenberg et al. “Quantitative analysis of apoptotic cell death using proton nuclear magnetic resonance spectroscopy.”BloodMay 15, 1997;89(10):3778-86.
Kasina et al. “Preformed chelate TC-99m radiolabeling of r-annexin V for arterial thromnus imaging.”J. Nuc. Med.1996;37(5):29.
Stratton et al. “Selective uptake of radiolabeled annexin V on acute porcine left atrial thrombi.”CirculationNov. 15, 1995;92(10):3113-21.
Babich, J.W., et al., “Technetium-99m-Labeled Hydrazino Nicotinamide Derivatized Chemotactic Peptide Analogs for Imaging Focal Sites of Bacterial Infection,”The Journal of Nuclear Medicine34(11):1964-1974 (1993).
Barrow, S.A., et al., “Localization of Indium-111-Immunoglobulin G, Technetium-99m-Immunoglobulin G and Indium-111-Labeled White Blood Cells at Sites of Acute Bacterial Infection in Rabbits,”The Journal of Nuclear Medicine34:1975-1979 (1993).
Bennett, M.R., et al., “Binding and Phagocytosis of Apoptotic Vascular Smooth Muscle Cells Is Mediated in Part by Exposure Phosphatidylserine,”Circ. Res.77:1136-1142 (1995).
Blankenberg, F.G., et al., “Detection of Apoptotic Cell Death by Proton Nuclear Magnetic Resonance Spectroscopy,”Blood87(5):1951-1956 (1996).
Koopman,G., et al., “Annexin V for Flow Cytometric Detection of Phosphatidylserine Expression on B Cells Undergoing Apoptosis,”Blood84(5): 1415-1420 (1994).
Reutelingsperger, C.P.M., and W.L. van Heerde, “Annexin V, the regulator of phosphatidylserine-catalyzed inflammation and coagulation during apoptosis,”Cell. Mol. Life Sci.53:527-532 (1997).
Schwartz, David A., et al. “Preparation of Hydrazino-Modified Proteins and Their Use for the Synthesis of .sup.99m Tc-Protein Conjugates,”Bioconjugate Chem.2: 333-336 (1991).
Tait, J.F., and C. Smith, “Site-Specific Mutagenesis of Annexin V:Role of Residues from Arg-200 to Lys-207 in Phospholipid Binding,”Archives of Biochem. and Biophys.288(1):141-144 (1991).
Tait, J.F., and D. Gibson, “Measurement of membrane phospholipid asymmetry in normal and sickle-cell erthrocytes by means of annexin V binding,”J.Lab. Clin. Med.123:741-748 (1994).
Tait, J.F., et al., “Phospholipid Binding Properties of human Placental Anticoagulant Protein-I, a Member of the Lipocortin Family,”The Journal of Biological Chemistry264(14):7944-7949 (1989).
Tait, J.F., et al., “Placental Anticoagulant Proteins: Isolation and Comparative Characterization of Four Members of the Lipocotrin Family,”Biochemistry27:6268-6276 (1988).
Tait, Jonathan F., “Clinical Applications of Annexins,”Annexins:Molecular Structure to Cellular Function, ed. Barbara A. Seaton, R.G. Landes Co., 1996, pp. 213-220.
van Heerde, W.L., et al., “The Complexity of the Phospholipid Binding Protein Annexin V,”Thrombosis and Haemostasis73(2):172-179 (1995).
Wood, B.R., et al., “Increased Erythrocyte Phosphatidylserine Exposure in Sickle Cell Disease: Flow-Cytometric Measurement and Clinical Associations,”Blood88(5): 1873-1880 (1996).
Zwaal, Robert F.A., and Alan J. Schroit, “Pathophysiologic Implications of Membrane Phospholipid Asymmetry in Blood Cells,”Blood89(15): 1121-1132 (1997).
Blankenberg Francis G.
Katsikis Peter D.
Strauss H. W.
Tait Jonathan F.
DeConti, Jr. Giulio A.
Laccotripe Zacharakis Maria
The Board of Trustees of the Leland Stanford Junior University
University of Washington
Yaen Christopher H.
LandOfFree
Method of imaging cell death in vivo does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of imaging cell death in vivo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of imaging cell death in vivo will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2749628